Do you have a higher threshold regarding when to hold bevacizumab for proteinuria in patients who had known baseline proteinuria from diabetic nephropathy?
Answer from: at Academic Institution
This is an interesting question. It’s not uncommon to have patients with cancer who have other underlying conditions that may lead to proteinuria. I don’t have a higher or lower threshold to recommend holding VEGF inhibitors, but in all patients who are on them who develop proteinuria, t...
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Answer from: at Academic Institution
I agree with Dr. @Anushree Shirali. Each patient has their associated comorbidities and their response to bevacizumab and availability of other therapeutic options do factor into the decision-making regarding tolerable levels of proteinuria. The proteinuria trend also factors into decision-making. I...