Nephrology

Lupus nephritis

Questions discussed in this category

Would you feel comfortable adding benlysta to patient already taking both mycophenolate and tacrolimus (and hydroxychloroquine) who still has some evidence of active lupus nephritis?

3 Answers available

Would you treat a patient aggressively for lupus nephritis if they have persistent proteinuria over 1 gram but cannot get a timely kidney biopsy?

3 Answers available

Is there a role for eculizumab in the management of refractory lupus nephritis?

3 Answers available

Do you routinely advise patients waiting for a kidney transplant to seek referrals at multiple institutions to decrease waiting time?

1 Answer available

What do you use for treatment induction in pure class V lupus nephritis with nephrotic-range proteinuria when MMF is contraindicated?

2 Answers available

In which clinical scenarios is relying on the urine protein-to-creatinine ratio as a measure of proteinuria unreliable, and interpretations should be made looking at urine protein and urine creatinine separately?

1 Answer available

What is your approach to using NIH activity and chronicity indices from renal biopsy in tailoring immunosuppression to a patient with new lupus nephritis?

3 Answers available

How do you approach the management of immunosuppression in patients with lupus nephritis that go on to dialysis?

3 Answers available

How do steroids and/or DMARDs affect biopsy results if a renal biopsy for suspected lupus nephritis is delayed?

1 Answer available

Papers discussed in this category

Kidney international, 2009-12

A prospective study of protein excretion using short-interval timed urine collections in patients with lupus nephritis.

Clinical journal of the American Society of Nephrology : CJASN, 2010-07

Comparison of urinary albumin-creatinine ratio and albumin excretion rate in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications study.

Journal of the American Society of Nephrology : JASN, 2010-08

Comparison of different measures of urinary protein excretion for prediction of renal events.

Am J Kidney Dis, 2016 Sep 16

Timed Urine Collections for Albumin and Protein: "The King Is Dead, Long Live the King!".

J Rheumatol, 2004 Aug

Urine protein-to-creatinine ratio is a reliable measure of proteinuria in lupus nephritis.

The American journal of medicine, 1983-09

Prognostic factors in lupus nephritis. Contribution of renal histologic data.

Arthritis care & research, 2011-06

Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring.

Kidney international, 2018-04

Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.

Kidney Int, 2010 Feb 24

Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system.

Rheumatology international, 2017 Mar 03

Expanding the therapeutic options for renal involvement in lupus: eculizumab, available evidence.

Rheumatology (Oxford, England), 2015 Aug 27

Eculizumab as rescue therapy in severe resistant lupus nephritis.

Arthritis and rheumatism, 2011-12

A phase III, randomized, placebo-controlled study of belimumab, a monoclonal antibody that inhibits B lymphocyte stimulator, in patients with systemic lupus erythematosus.

N Engl J Med,

Two-Year, Randomized, Controlled Trial of Belimumab in Lupus Nephritis.

Lupus,

Hydroxychloroquine use predicts complete renal remission within 12 months among patients treated with mycophenolate mofetil therapy for membranous lupus nephritis.

Arthritis Rheumatol, 2017 Apr 07

Efficacy and Safety of Subcutaneous Belimumab in Systemic Lupus Erythematosus: A Fifty-Two-Week Randomized, Double-Blind, Placebo-Controlled Study.

Lancet (London, England), 2011 Feb 04

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial.

Lupus Sci Med, 2018

Serum albumin at 1 year predicts long-term renal outcome in lupus nephritis.

Nephrology

Lupus nephritis

Questions discussed in this category

Papers discussed in this category

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