Dermatology

Psoriasis

Questions discussed in this category

What are the best biologics for a pediatric patient with extensive guttate psoriasis that is poorly controlled on topicals?

Mother's insurance plan has a high deductible and phototherapy is inconvenient (family lives 50 minutes away).

2 Answers available

How do you approach patients that develop atopic dermatitis while on biologics for psoriasis?

I have an elderly patient with a history of biopsy-proven psoriasis on IL-17 biologic therapy. She has developed an intense itch without a primary ras...

1 Answer available

How do you approach managing nausea and GI side effects when initiating methotrexate?

2 Answers available

What lab monitoring and frequency do you recommend in an otherwise healthy young patient on biologics for psoriasis?

With no high-risk exposure do you repeat quant gold?

4 Answers available

How do you approach management of patients with psoriatic arthritis who have significant improvement in skin disease, but ongoing inflammatory arthritis despite multiple DMARDs and/or biologics?

1 Answer available

Do you avoid the use of hydroxychloroquine in patients with psoriasis and/or psoriatic arthritis?

2 Answers available

Would you consider using a JAK inhibitor in combination with an IL 23 inhibitor in cases of severe psoriasis, psoriatic arthritis, or axial spondyloarthritis that is refractory to multiple biologic DMARDs?

2 Answers available

What topical therapies do you find are most effective for treating inverse psoriasis in areas of the body with thinner skin?

4 Answers available

How do you manage patients on biologics peri-operatively?

Are there any medications that surgeons like discontinued before their procedure?

1 Answer available

What is your approach to using apremilast for psoriatic arthritis in patients with history of depression?

1 Answer available

What is your approach to a young adult patient with significant nail psoriasis and not much cutaneous disease?

1 Answer available

How do you manage psoriasis in pregnant patients?

3 Answers available

How do you approach restarting biologics for psoriasis patients who have discontinued therapy for 3-6 months?

Do you prefer restarting the biologic with the loading or maintenance dosing?

1 Answer available

Is it ever reasonable to switch to a different TNFi as opposed to switching to an agent in a different class in a case of TNFi induced lupus or psoriasis?

In other words, do we think of TNFi induced lupus and TNFi induced psoriasis as a drug effect or a class effect?

1 Answer available

What treatment options are available for patients with spondyloarthritis who develop biologic-induced psoriasis?

1 Answer available

Papers discussed in this category

Journal of psoriasis and psoriatic arthritis, 2019-04

TNF Inhibitor-Induced Psoriasis: Proposed Algorithm for Treatment and Management.

Front Pharmacol, 2019 Mar 26

Paradoxical Skin Reactions to Biologics in Patients With Rheumatologic Disorders.

Seminars in arthritis and rheumatism, 2010-12

Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: clinical features and possible immunopathogenesis.

Clin Exp Rheumatol, 2012 Oct 17

Anti-tumour necrosis factor alpha therapy and increased risk of de novo psoriasis: is it really a paradoxical side effect?

Inflamm Bowel Dis,

Tumor necrosis factor α antagonist-associated psoriasis in inflammatory diseases: an analysis of the FDA adverse event reporting system.

Am J Clin Dermatol,

Tumor necrosis factor-alpha inhibitor-induced psoriasis or psoriasiform exanthemata: first 120 cases from the literature including a series of six new patients.

JAMA Dermatol,

Pregnancy Outcomes in Women With Moderate-to-Severe Psoriasis From the Psoriasis Longitudinal Assessment and Registry (PSOLAR).

The Journal of rheumatology, 2012-01

Combination biologic treatment of refractory psoriasis and psoriatic arthritis.

JAAD Case Rep, 2019 Oct 10

Dual biologic therapy for recalcitrant psoriasis and psoriatic arthritis.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 2023 Feb 11

Eczematized psoriasis - a frequent but often neglected variant of plaque psoriasis.

Clinical rheumatology, 1988 Sep

Treatment of psoriatic arthritis with sulphasalazine: a one year open study.

Journal of the American Academy of Dermatology, 1987 Apr

Gold therapy and its indications in dermatology. A review.

Journal of the American Academy of Dermatology, 2020 May 19

Hydroxychloroquine effects on psoriasis: A systematic review and a cautionary note for COVID-19 treatment.

Annals of the rheumatic diseases, 2018-09

Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study.

Arthritis & rheumatology (Hoboken, N.J.), 2019-02

Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis.

RMD open, 2020 Feb

Effects of ustekinumab on spondylitis-associated endpoints in TNFi-naïve active psoriatic arthritis patients with physician-reported spondylitis: pooled results from two phase 3, randomised, controlled trials.

Trials, 2022 Sep 05

Efficacy and safety of guselkumab in biologic-naïve patients with active axial psoriatic arthritis: study protocol for STAR, a phase 4, randomized, double-blinded, placebo-controlled trial.

Dermatology

Psoriasis

Questions discussed in this category

Papers discussed in this category

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